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Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional

Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 300-309 doi: 10.1007/s11684-014-0357-8

Abstract: clinical research observation, and analysis and data mining via computer and database technologies.The advent of the big data era as well as the formation and practice accumulation of the TCM clinicalresearch paradigm in the real world have provided new perspectives, techniques, and methods for inheritingThrough continuous exploration and practice, the research group proposes the innovation research modebased on the real-world TCM clinical research paradigm, which involves the inheritance and innovation

Keywords： traditional Chinese medicine (TCM) real world clinical research paradigm famous specialist experience

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Clinical acupuncture research in the West

Xianze Meng, Shifen Xu, Lixing Lao

Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 134-140 doi: 10.1007/s11684-011-0135-9

Abstract: acupuncture has rapidly become part of mainstream medicine in the West, where new developments in acupuncture clinicalresearch show extensive progress in evaluating the efficacy and safety of the modality in many categoriesAlthough challenges and difficulties remain, the acupuncture research community has matured and its pastexperience may lead to even better methods and more innovative research.

Keywords： acupuncture clinical research research methodology the West

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Construction of a shared system-based real-world clinical research system

Huikun Wu,Xiaodong Li,Fan Yang,Dan Xie,Hui Li,Jingjing Huang,Mingxing Guo

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 382-388 doi: 10.1007/s11684-014-0368-5

Abstract:

Hubei Provincial Hospital of Traditional Chinese Medicine established research outpatient clinicsClinical Research Base and to the construction of the National Traditional Chinese Medicine Treatmentand Clinical Research Information Sharing System.With a view of developing a “real-world traditional Chinese medicine clinical research paradigmof clinical research, health management, and characteristics diagnosis and treatment.

Keywords： clinical research shared system real world research outpatient clinic research hospital

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Clinical research of traditional Chinese medicine in big data era

Junhua Zhang,Boli Zhang

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 321-327 doi: 10.1007/s11684-014-0370-y

Abstract: Data-intensive scientific discovery based on big data, named “The Fourth Paradigm,” has becomea new paradigm of scientific research.research and assessment.Our research target shifts from the “causality inference” to “correlativity analysisTo conduct clinical studies involved in big data in TCM domain, top level design is needed and should

Keywords： big data traditional Chinese medicine clinical evaluation evidence based medicine

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Scientific computation of big data in real-world clinical research

Guozheng Li,Xuewen Zuo,Baoyan Liu

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 310-315 doi: 10.1007/s11684-014-0358-7

Abstract: It also discusses the integration of science, technology, and medicine under the guidance of the paradigmof real-world, clinical scientific research.TCM clinical diagnosis, treatment, and knowledge were traditionally limited to literature and sensationmethods are applied in the modeling and analysis of the various complex relationships in individualized clinicalThus, these methods strongly support the real-world clinical research paradigm of TCM.

Keywords： big data real world clinical research Chinese medicine medical computing

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Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer researchand a new co-clinical model for treatment optimization

Shuyang Sun,Zhiyuan Zhang

Frontiers of Medicine 2016, Volume 10, Issue 1, Pages 104-110 doi: 10.1007/s11684-016-0432-4

Abstract: of their donor tumors have been shown to be the preferred preclinical tool in translational cancer researchestablished and characterized an OSCC PDX panel as part of our tumor bio-bank for translational cancer researchWe also explore the translational value of this well-annotated PDX panel in the development of co-clinical

Keywords： patient-derived xenograft models personalized medicine co-clinical trial patient stratification oral

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Overcoming the challenges of conducting translational research in cell therapy

Sowmya Viswanathan, Armand Keating

Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 333-335 doi: 10.1007/s11684-011-0166-2

Abstract: but despite its considerable impetus, faces numerous challenges including support for translational researchHere, we examine the challenges confronting cell therapy research including the limited funding availablefor translational research partly due to the uncompetitive nature of required validation studies in

Keywords： stem cells clinical trials funding animal models standardization common definitions

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Basic consideration of research strategies for head and neck cancer

Jin Gao, Ben Panizza, Newell W. Johnson, Scott Coman, Alan R. Clough

Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 339-353 doi: 10.1007/s11684-012-0213-7

Abstract: of aetiology, key risk factors related to the development of head and neck cancer, basic features of clinicalWe also suggest basic research strategies on the basis of current knowledge, which should ultimatelylead to the improvement of clinical management.

Keywords： clinical management head and neck cancer prevention and early detection research strategies risk factors

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Clinical data quality problems and countermeasure for real world study

Runshun Zhang,Yinghui Wang,Baoyan Liu,Guangli Song,Xuezhong Zhou,Shizhen Fan,Xishui Pan

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 352-357 doi: 10.1007/s11684-014-0351-1

Abstract:

Real world study (RWS) has become a hotspot for clinical research.Data quality plays a vital role in research achievement and other clinical research fields.

Keywords： real world study traditional Chinese medicine clinical and research information sharing system data quality

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Research Status and Future Prospects of Intelligent Manufacturing Evaluation Theory

He Huixia, Wei Guiying, Wu Sen, Shan Zhiguang

Strategic Study of CAE 2022, Volume 24, Issue 2, Pages 56-63 doi: 10.15302/J-SSCAE-2022.02.026

Abstract: investigates the major problems regarding intelligent manufacturing evaluation and discusses the future researchIt is necessary to improve the evaluation paradigm, evaluation system, and new technology integration, so as to promote the research of intelligent manufacturing evaluation theories and guide the developmentSpecifically, China should improve the standards design to establish an intelligent manufacturing evaluation paradigm

Keywords： intelligent manufacturing evaluation theory index system evaluation paradigm new technology integration

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Optimizing the Roadmap to Carbon Neutralization with a New Paradigm

Wen Lai Huang, Jinghai Li

Engineering 2021, Volume 7, Issue 12, Pages 1678-1679 doi: 10.1016/j.eng.2021.09.005

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Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 358-361 doi: 10.1007/s11684-014-0348-9

Abstract:

This study proposes the ontological reconstruction of the current clinical terminology of traditionalof preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinicalWe conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation

Keywords： ontology traditional Chinese medicine clinical terminology

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Methodological challenges to human medical study

Yixin Zhong,Baoyan Liu,Hua Qu,Qi Xie

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 328-336 doi: 10.1007/s11684-014-0359-6

Abstract:

With the transformation of modern medicinal pattern, medical studies are confronted with methodological challenges. By analyzing two methodologies existing in the study of physical matter system and information system, the article points out that traditional Chinese medicine (TCM), especially the treatment based on syndrome differentiation, embodies information conception of methodological positions, while western medicine represents matter conception of methodological positions. It proposes a new way of thinking about combination of TCM and western medicine by combinating two kinds of methodological methods.

Keywords： medical paradigm traditional Chinese medicine western medicine scientific view scientific methodology

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Science for This Age: Paradigm Shifts and Global Challenges

Chao Dong, Jinghai Li, Daya Reddy

Engineering 2022, Volume 19, Issue 12, Pages 22-23 doi: 10.1016/j.eng.2022.05.002

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The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 527-533 doi: 10.1007/s11684-022-0967-5

Abstract: In this study, we aim to elucidate the clinical impact and long-term course of tricuspid regurgitation

Keywords： orthotopic heart transplant tricuspid regurgitation clinical impact biatrial heart transplantation

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Title Author Date Type Operation

Experience inheritance from famous specialists based on real-world clinical research paradigm of traditional

Guanli Song,Yinghui Wang,Runshun Zhang,Baoyan Liu,Xuezhong Zhou,Xiaji Zhou,Hong Zhang,Yufeng Guo,Yanxing Xue,Lili Xu

Journal Article

Clinical acupuncture research in the West

Xianze Meng, Shifen Xu, Lixing Lao

Journal Article

Construction of a shared system-based real-world clinical research system

Huikun Wu,Xiaodong Li,Fan Yang,Dan Xie,Hui Li,Jingjing Huang,Mingxing Guo

Journal Article

Clinical research of traditional Chinese medicine in big data era

Junhua Zhang,Boli Zhang

Journal Article

Scientific computation of big data in real-world clinical research

Guozheng Li,Xuewen Zuo,Baoyan Liu

Journal Article

Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer researchand a new co-clinical model for treatment optimization

Shuyang Sun,Zhiyuan Zhang

Journal Article

Overcoming the challenges of conducting translational research in cell therapy

Sowmya Viswanathan, Armand Keating

Journal Article

Basic consideration of research strategies for head and neck cancer

Jin Gao, Ben Panizza, Newell W. Johnson, Scott Coman, Alan R. Clough

Journal Article

Clinical data quality problems and countermeasure for real world study

Runshun Zhang,Yinghui Wang,Baoyan Liu,Guangli Song,Xuezhong Zhou,Shizhen Fan,Xishui Pan

Journal Article

Research Status and Future Prospects of Intelligent Manufacturing Evaluation Theory